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Pharmacological inhibition of PDHK1 using dichloroacetate (DCA) or knockdown of PDHK1 promotes Treg cell differentiation at the expense of Th17 cells [118,119,120,121]

For instance, (Sharifi et al., 2020), used a liver-chip model to evaluate and compare anticancer activity of thymoquinone from Nigella sativa , both in its free form and encapsulated in chitosan-based nanoparticles