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The toxicity of -synuclein is also responsible for impaired endoplasmic reticulum affecting also closely associated and functionally related Golgi apparatus, aggregation of anti-apoptotic proteins, and formation of pores in cellular membranes (Cooper et al

Carcinogenesis 27:20382046 Huang C, Ma WY, Li J et al (1998) Essential role of p53 in phenethyl isothiocyanate-induced apoptosis