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Concerns regarding the practicality and rationality of in vivo experiments on laboratory animals have been raised by medical experts, given the considerable anatomical and physiological differences between laboratory animals and humans

La radioterapia tambin se puede usar para lesiones que recidivan despus de un abordaje quirrgico primario.[23] Se evita administrar radioterapia a pacientes con afecciones que los predisponen a cnceres inducidos por radiacin, como el xeroderma pigmentoso o el sndrome del nevo basocelular