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[DOI] [PMC free article] [PubMed] [Google Scholar] 778.Asaoka D, et al

Similarly, Pb 2 can substitute for Ca 2 in cell wall stabilization and intracellular signaling, resulting in chlorosis, necrosis, and biomass reduction

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As a result of alterations in the inflammatory microenvironment and oncogenic mutations, sustained NF-B activation and dysregulation of cellular functions are observed in cancer, leading to genomic instability and gene mutations, creating a microenvironment that promotes tumor progression and promotes proliferation and angiogenesis of tumor cells while inhibiting their apoptosis