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Thus, the different expression of receptors on the apical and basolateral membranes can be considered as a kind of molecular mechanism that allows to avoid of excessive stimulation by luminal microbes

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doi: 10.1016/j.celrep.2020.107679 247 NajibiAJLaneRSSobralMCBovoneGKangSFreedmanBRet al

In a recent study, abnormal levels of cannabinoid receptor 2 (CB2r) and related endocannabinoid enzymes were found in the brain and peripheral blood mononuclear cells (PBMCs) of X-ALD patients and in the spinal cord of a murine model of X-ALD