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GWAS studies identified multiple NAFLD-associated genetic variants in large cohorts with NAFLD phenotypes based on clinical and radiological data

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Partridge, M

In particular, upon administration in mice, only the mono-glutathionylated adducts were not toxic to kidneys, while a correlation was recorded between the number of glutathione substitutions and the nephrotoxicity observed [83]

However, its clinical use is still in early stages, with ongoing studies focused on optimizing phage selection, delivery methods, and safety (Ranveer et al., 2024)