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Synergism through combination of chemotherapy and oxidative stress-induced autophagy in A549 lung cancer cells using redox-responsive nanohybrids: a new strategy for cancer therapy

10.21037/atm-2019-rcs-04 Ann Transl Med

, I, J, K and M), the signals observed for thiomethyl metabolites were equivalent or higher than the ones observed for free APAP, indicating that a high proportion of reactive NAPQI was generated in these patients, and then reabsorbed into the systemic circulation before being eliminated