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This is often achieved through the activation of the transcription factor nuclear factor erythroid-2-related factor 2 (NRF2), which subsequently triggers the expression of various antioxidant enzymes, including superoxide dismutases (SODs), peroxiredoxins (Prxs), catalase (CAT), and glutathione peroxidases (GPxs)

It is present in virtually every cell of the body, where it acts as a primary shield against free radicals

FIGURE 6 Given the mechanisms of infection by both SARS-CoV-2 and Cpn, the possibility that a long-term co-infection could exacerbate the neuroinflammation seen individually for each organism could be likely

Q7A: Good manufacturing practice guidance for active pharmaceutical ingredients