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Furthermore, 6-, 8-, and 10-gingerols administered at a dose of 0.15 mol/L each to human T cells in an in vitro model for 48 h demonstrated an enhancement in inflammatory cytokine levels compared to T cells that were not given gingerols intervention

In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls