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This study was funded by the Zhenjiang Key Research and Development Plan (social development) (Grant No

was funded by the Consejo Nacional de Ciencia y Tecnologa Mexico (postdoctoral fellowship 232510.), M.T.A

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These results show that in redox-compromised MnSOD-deficient yeast cells, but not in wild-type cells, aspirin starves the mitochondria of acetyl-CoA and likely causes energy failure linked to mitochondrial damage, resulting in cell death