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Author contributions RX, JP and MG conceived and designed the experiments, drafted, and revised the manuscript

These diseases show a strong association with HLA-B27, but the strength of this association varies among these various forms and among some of the racial/ethnic groups worldwide

Studies have suggested that L-cysteine supplementation can help reduce the symptoms of ulcerative colitis, an inflammatory bowel disease that causes long-lasting inflammation and sores in the digestive tract

Only a few studies measured markers of oxidative stress (malondialdehyde (MDA), superoxide dismutase (SOD) and catalase) and reported mixed results