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SKU: 1600908094
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Rating: 4.371700000000001 (10 reviews)

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Description

Double strand DNA activates endosomal TLR9, or RNAs activate cytosolic nucleic acid sensors MDA5 or RIG-1, all of which result in activation of IRF7

Axonal damage and glial response accompanying demyelination were more severe and prolonged in aged (67 months) as compared to young (810 weeks) mice (Irvine and Blakemore, 2006)