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Don't overthink this part too much, but first is generally best

doi:10.1016/j.pnpbp.2018.06.005 94 Li, F

The system prepared hyaluronic acid/gelatin/sodium alginate hydrogel loaded with NAC-modified gold nanoclusters (NAC-Au NCs) by 3D printing technology (N-Au@hydrogel) and combined with biological hydrogel-encapsulated hepatocyte spheroids containing acellular liver matrix (dECM), thrombin and fibrinogen (HS@dECM) [Figure 4A]