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Finally, while our results consistently demonstrate that Se/LDH@PEG-M modulates the macrophage population by suppressing M1 markers and enhancing M2 traits, it remains to be definitively verified whether this represents a direct phenotypic reprogramming of existing M1 macrophages into M2 macrophages

The agency warned that injectable products, which could include glutathione, vitamin C, collagen and even human placenta, were "potentially unsafe and ineffective, and might contain unknown harmful ingredients or contaminants"

B-vitamins are commonly administered intravenously as well with great effect

This molecular-level design strategy effectively overcomes the inherent limitations of conventional static biomaterials (Table 3)