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N6F11, the first of its kind, activates the tumor cell-specific protein TRIM25, which indirectly induces GPx4 degradation, uniquely inducing ferroptosis only in tumor cells without affecting immune cells and enhancing the therapeutic efficacy of immune checkpoint inhibitors

Luseogliflozin-mediated improvement in dysfunctional fatty acid oxidation Because luseogliflozin treatment in I/R-injured kidneys activated ketone body metabolism, but did not reduce the levels of pAMPK and Sirt3, which are involved in fatty acid oxidation, we next evaluated the effects of luseogliflozin on fatty acid oxidation

Additionally, miR-302b-3p may inhibit gene expression by targeting antioxidant enzyme genes, such as superoxide dismutase 2 and catalase

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