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They can express major histocompatibility complex (MHC) class I and II antigens, that is why the DCs enable to activate both CD4+ helper and CD8+ cytotoxic T cells

It is difficult to say if B12 is the cause

Our data extends on these findings, revealing an increase in 4-HNE expression within all ovarian cell types upon maternal ageing, including a pronounced accumulation within oocytes and granulosa cells