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Here are three suitable alternatives, each offering its own set of advantages: 1

As many treatments for neurological conditions have been hampered by limited permeability of the BBB, significant emphasis has been placed on research directed towards advanced drug delivery methods (Liu et al., 2025)

The greater severity of liver damage in NASH may make improvements more detectable and statistically significant

GSH is synthesized in a two-step reaction catalyzed by -glutamylcysteine synthetase and GSS in the -glutamyl cycle, which includes an additional four enzymes (Figure 1)