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Researchers utilize this peptide to examine how modulated GH/IGF-1 axis activity influences muscle protein synthesis, lipolysis, and metabolic regulation in experimental models, with particular focus on its reduced impact on cortisol and prolactin compared to other secretagogues

244,245 DJ-1 also binds to the DNA-binding domain of p53, diminishing the DNA-binding affinity of p53 and inhibiting the expression of p53 target genes in a manner that relies on the oxidation of cysteine 106