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Study design should reflect that gap

Based on the importance of identifying biochemical correlates, this study investigated GSH levels, CD4 and CD8 lymphocyte counts, and their associations with perceived stress, anxiety and depression symptoms, self-esteem, and socio-familiar support in young adults without a prior clinical diagnosis

Its core regulatory componentsProtein Kinase RNA-like ER Kinase (PERK), Inositol-Requiring Enzyme 1 (IRE1), and Activating Transcription Factor 6 (ATF6), coordinate signaling networks to respond to environmental stress (Rahmani et al., 2023)

Furthermore, the thiol group involved in cysteine structure has high heavy metal affinity (Piste, 2013)