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Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

Since glutathione and pyruvate are antioxidants, glycolytic inhibition limited cells reductive capacity and increased their susceptibility to oxidative stress

The novel Bach1 inhibitor HPP971 uniquely activates Nrf2 and reduces disease severity in a mouse model of experimental autoimmune encephalomyelitis

It is commonly employed as a diluent for the reconstitution of lyophilized peptides prior to analytical, in-vitro, or other non-clinical laboratory studies