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In studies on melanoma cells in vitro and in vivo , elevated GGT activity has been found to accompany an increased invasive growth [45, 47, 48], and a positive correlation has been described between GGT expression and unfavourable prognostic signs in human breast cancer [49]

Tumor cell viability assay Cells (2.5 10 4 ) were plated in a 96-well white edged plate and treated with various concentrations of RSL3 (0.0052.0 M) or DMSO for 48 h

The amount of Ig captured depends on the concentration of Ig in the starting sample and on the type and source of the Ig

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