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A host-gut microbial co-metabolite of aromatic amino acids, p-resol glucuronide, promotes blood-brian barrier integrity in vivo

Powell-Wiley TM, Poirier P, Burke LE, et al

L'ARA-290 (cibinetide) is an 11-amino-acid peptide that selectively activates the EPO-R/CD131 (innate repair receptor) complex without stimulating erythropoiesis or increasing hematocrit