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Additionally, mTOR is localized in spinal cord microglia, and puerarin increases the expression of the ferroptosis marker protein GPX4, suggesting that puerarin may alleviate chronic postsurgical pain by inhibiting mTOR phosphorylation, thereby suppressing ferroptosis in microglia

R.MarsdenC

By establishing ecological dominance and selectively reshaping microbial composition, probiotics lay the microecological foundation for subsequent barrier repair and immune regulation