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Reduces inflammation : Chronic inflammation is one of the underlying causes of many skin conditions, including acne, rosacea, and eczema

10.1074/jbc.271.19.11039 55

Targeting PI3K pathway with Copanlisib along with ADT reduces lactate secretion and, thus, tumor growth repression helped by immunosuppression of activated TAMs in a PTEN/p53-deficient murine PC model [140]