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RMSD analysis (Fig

Therefore, increasing PDI S -nitrosylation (such as by treating the HT22 cells with SNAP) was shown to prevent glutamate- or erastin-induced cell death [8, 9]

By contrast, disruption of the Arf1-mediated lipolysis pathway or the acetyl-CoA carboxylase 1 (ACC1)-mediated de novo fatty acid synthesis pathway resulted in a marked decline in ISCs 7,18