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The study hypothesized that OS affects the MMP/TIMP balance and interferes with the TGF-1/Smad pathway, reducing elastic fibre formation and diminishing pelvic floor support, ultimately resulting in POP

Mizoguchi et al .[] and Papanikolaou et al .[] observed that Salmonella typhimurium and Salmonella dublin -induced colitis on mice shows inflammation similar to histopathological characteristics to human UC, including epithelial crypt loss, erosion, and neutrophil inflltration

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