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Leleu X, Terpos E, Sanz RG, Cooney J, OGorman P, Minarik J, et al

(2025) Nat Metab, 7: 895

Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs

The mechanistic elucidation advances TNBC therapeutic development, offering a multi-dimensional targeting strategy against this recalcitrant malignancy