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doi: 10.1155/2018/1874985 27 ZhangQJuYMaYWangT

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The available data, however, are limited and inadequate to reliably quantify sex-related differences in toxicity

For example, inhibition of phosphofructokinase-1 leads to the accumulation of fructose 6-phosphate, which, via the phosphoglucose isomerase reaction, increases glucose 6-phosphate levels