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Description

It blocks the protein CXXC5 from suppressing the Wnt/beta-catenin signaling pathway , which is essential for hair follicle growth, stem cell activation, and follicle neogenesis

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(55) found that the blood lipocalin-2 (LCN2) and serum amyloid A (SAA) levels may be associated with a type 17 asthma subtype, which are steroid-resistant IL-17A target genes in airway cells, and IL-17AAct1/CEBPB axis is an important regulatory mechanism of LCN2 and SAA