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Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, et al

Recent enzymatic analyses in lymphocytes showed that BD patients in the depressive phase had lower levels of mitochondrial complex II activity compared to those in the euthymic phase, with a significant negative correlation between the Hamilton Depression Rating Scale score and mitochondrial complex II activity [50], providing a strong link between reduced mitochondrial function and current bipolar depressive phase

Exercising artistic license here, the below graph with the lilac-shaded area at the right takes the Morning point (A) point and replays it at the right end of the graph as (A*)

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