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To resolve this limitation but maintain budget neutrality within the ASC payment system, we multiplied the change in the geometric mean costs of covered surgical skin procedures in the ASC setting from unpackaging skin substitute products by the utilization of such skin procedures in the ASC setting to approximate the estimated skin substitute payments in the ASC setting

Below they are set out separately with the name of the pathway and the practical translation observed in research models

Russell, M

Phase 2 Type 2 Diabetes Trial Rosenstock et al., The Lancet (2023) Rosenstock and colleagues conducted a phase 2, randomized, double-blind, double-dummy, placebo-controlled and active-comparator-controlled, parallel-group trial of retatrutide in adults with type 2 diabetes