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The study showed an absolute 5.5% smaller myocardial infarct size in NAC-treated patients compared with placebo-treated patients (16.5% versus 11.0% size reduction, p = 0.02)

To boost pegtibatinase stability and minimize unwanted protein aggregation, a cysteine-to-serine substitution at position 15 is introduced to prevent the formation of interdimer disulfide bonds