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Enzymatic studies of alcohol dehydrogenase by a combination of in vitro and in silico methods, PhD thesis (PDF)

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Upon binding to DNA strand breaks, PARP transfers ADP-ribose units from the respiratory coenzyme nicotinamide adenine dinucleotide (NAD + ) to various nuclear proteins (e.g., DNA polymerase, histones, and an automodification domain of PARP itself), building up large ADP-ribose polymers that may reach up to 200 units (1150)

Consequently, the data gathered earlier using the functional mimic FhbA, which potentially indicated a non-specific interaction between aptamers and others Borrelia surface proteins, could be considered as negligible