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The present paper discusses if a combination of the extracellularly distributed DMSA with the ionophore, Monensin may provide a less toxic combination for Pb mobilization by increasing both the efflux of intracellularly deposited Pb and the urinary Pb excretion

1f,g), in contrast to Mx1-T3 mice, which were protected from cytokine production (Fig

Moreover, in triple-negative breast cancer (TNBC), studies have shown that resistance to RSL3-induced ferroptosis can be significantly reversed by the irreversible HER2 inhibitor Neratinib, and this effect is dependent on Neratinib-induced mitochondrial ROS production and DNA replication stress, thereby increasing cellular sensitivity to ferroptosis (134)

Our results showed a significant increase in intracellular GSH content in cells treated with 100 M of -EC, GSH, or UDE containing 100 M -EC, compared to the untreated control cells (Fig