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These data are supported by a proof-of-concept trial that randomized CIPN patients to a wirelessly controlled TENS unit or control and concluded that TENS can provide benefit for treatment of pain and cramping from CIPN (Gewandter 2024)

( in-situ hydrogel (NCs-AS-ALG) composed of alginate cross-linked with CuFe 3 O 4 nanoclusters (NCs) and artesunate (AS)

The lymphatic system clears cellular debris, inflammatory cytokines, and environmental particulates from tissues and returns them to the circulatory system for processing

Treatment with clomipramine hydrochloride and any concomitant serotonergic agents should be discontinued immediately if the above events occur and supportive symptomatic treatment should be initiated