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Interestingly, in one study, the authors used metformin, which activates AMPK and autophagy, and it was studied in diabetic patients to improve insulin sensitivity and lipid metabolism

The contribution of ferroptosis to CRC was first suggested by Sui et al

Our genomic and transcriptomic analyses identified 8 genes in the Se metabolic pathway: sulfate transporter ( SULTR ), 3-phosphoadenosine 5-phosphosulfate synthase ( PAPSS ), adenylylsulfate reductase ( APR ), sulfite reductase ( SiR ), cysteine synthase ( cysK ), cystathionine gamma-synthase ( metB ), methionine synthase ( MetE ), and met S-methyltransferase ( MMT ) (Fig