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Lactate could increase the concentration of the components of the malateaspartate shuttle, which increases the rate of transport of reducing equivalents to the mitochondrial matrix [178]

Most studies focus on short-term use 2

Metabolic rewiring of bacterial pathogens in response to antibiotic pressurea molecular perspective

Particularly noteworthy, mechanical overload can activate the mechanosensitive ion channel Piezo1, mediating calcium influx, which subsequently triggers the downstream GPX4-regulated ferroptosis pathway (Yao et al., 2021