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We explore the evidence, the limitations, and why movement remains one of the most powerful tools for recovery

Expert Opin Ther Pat 30(6):389407

10.1038/nrneurol.2016.133 30 CampbellM.FishB.ShapiroT.FloydA.Jr

Accordingly, for clinical-stage PROTACs, selectivity is more appropriately understood primarily at the levels of target engagement and degradation profile, whereas strict cell-type selectivity is not generally considered an intrinsic property