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Some of these medications are applied directly to the genital region, while others are taken by mouth

Influence of body condition score on relationship between metabolic status and oxidative stress in periparturient dairy cows

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Interestingly with Chen et al, it was noted that those reported improvement had low urinary nitrite/nitrate, the excreted metabolic products of NO, suggesting that those with low NO levels are more likely to improve with L-arginine supplementation