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Collectively, while these findings establish an important role for NUPR1 in bronchial cell viability, they provided no evidence for CS-induced activation of NUPR1 in vitro and thus do not support a specific role for NUPR1 in protecting bronchial epithelial cells from CS exposure-induced cell death

Patients on stimulant medications at screening were allowed to continue and maintain current stimulant doses during the trial provided that doses were clinically stable

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first found the lipid-lowering effect of cynaroside, but they gave a complex plant extract and did not detail the proportion of active ingredients