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DNA Cell Biol 39(8):14671472

Results depend on the size, location, and age of the lesion

In complementary studies, depletion of MFN1/2 found similar hyperglycemia, reductions in insulin secretion, and mitochondrial network fusion and respiration, however, these effects correlate more with effects on mitochondrial DNA (mtDNA) content rather than changes in fission/fusion (Sidarala et al., 2022)