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Recent studies have shown that mitochondria-targeted nanoinducers (mitoNIDs) can selectively impair mitochondrial function in cancer cells, disrupting energy metabolism and redox balance [89]

Walker, B.J., Long, J.B., Sathyamoorthy, M., Birstler, J., Wolf, C., Bosenberg, A.T., Flack, S.H., Krane, E.J., Sethna, N.F., Suresh, S

2.8 CCK-8 assay HUVECs were evenly seeded into 96-well plates at a density of 1 10^4 cells per well, with a culture medium volume of 100 L per well

Nevertheless, it is reasonable to assume that if these 2 RCTs were removed, the effect sizes for the early outcomes and the study endpoint outcomes (Table 1) would drop and perhaps even lose statistical significance