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The animal studies used both local application at the injury site and systemic administration (intraperitoneal and intragastric), with both routes showing significant effects

Luciferase and renilla signals were measured 48 h after transfection using the Dual Luciferase Reporter Assay Kit (Promega, Madison, WI, USA) according to a protocol provided by the manufacturer

While LPS exposure alone resulted in a 59% increase in oxidized DCF (a measure of ROS) compared to control cells, pretreatment with GHK-Cu at concentrations of 1, 5, and 10 M significantly decreased ROS production

In Zukunft werden weitere Studien untersuchen, ob sich hier die verbesserte Spermienqualitt auch auf die Schwangerschaftsrate positiv auswirkt