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Recent research has shown that controlling ROS production through antioxidants can restore mitochondrial biogenesis and improve renal function, providing an innovative therapeutic strategy for these pathologies (Guo et al

Amyotrophic lateral sclerosis The motor neuron injury in ALS is thought to arise from multiple interacting pathophysiological mechanisms, including glial dysfunction and neuroinflammation

72,73 Together, these results show that BDNF and, to some extent, the upstream CREB signaling pathway contribute to the neuroprotective effect associated with synaptic excitotoxicity in cerebral ischemia