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Using this invasive technique, intra-arterial infusion of lipoic acid was found to improve endothelium-dependent vasodilation in 39 subjects with type 2 diabetes but not in 11 healthy controls (62)

Dose: 0.25mg daily for weeks 1-2, increased to 0.5mg daily for weeks 3-6 Administration: Subcutaneous injection, rotating between deltoid area and upper chest near the shoulder Duration: 6 weeks total Supporting therapy: Light stretching daily, avoided overhead movements until week 4 Three months out from finishing the protocol, my shoulder still feels solid

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10.1194/jlr.M300179-JLR200 72