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doi: 10.1007/s44187-024-00199-0 11 BampiS

Discovery of highly potent and selective thyroid hormone receptor agonists for the treatment of nonalcoholic steatohepatitis

The above results indicated that the T-BPH rat model was successfully established, and the prostate of T-BPH rats showed accelerated proliferation activity, decreased apoptosis, shortened G0/G1 phase and down-regulated GPX3 expression, all of which could be reversed by TRO treatment