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doi:10.20452/pamw.4287 Orme R, Judge HM, Storey RF

However, there have been cases of people breaking out into acne and rosacea and having heart palpitations after taking very high doses of vitamin B12, usually by injection

Natural sources include: Because plants do not synthesize Vitamin B12, individuals following plant-based diets must rely on: This microbial origin underscores an important biological principle: the human requirement for Vitamin B12 reflects an evolutionary dependence on symbiotic or environmental microbial synthesis

Researchers observed that intragastric administration was associated with maintained mucosal integrity and altered expression of growth factors compared to vehicle-treated controls [3]