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Migration index and migration rate were also calculated using the following 2 equations respectively: [25] MNs fabrication MNs were prepared using micro-molding technology with a polymeric matrix composed of 20% w/w PVA, 25% w/w PVP, and 0.5% w/w propolis, based on a previously reported method with minor modifications [26]

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Among the aforementioned cell death modalities, ferroptosis is morphologically most similar to necroptosis, but it can be clearly distinguished based on characteristic biomarkers such as 4-HNE, MDA, and changes in GPX4 expression