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A commonly used regimen is a loading phase of 25 mg per week (subcutaneous injection) for 46 weeks, followed by a maintenance dose of around 2 mg every 12 weeks

Correlations between gene modules and experimental conditions (genotype or treatment) were tested using the limma R package, with multiple testing corrections via the BenjaminiHochberg method

Whistler JL, Chuang HH, Chu P, Jan LY, von Zastrow M: Functional dissociation of mu opioid receptor signaling and endocytosis: Implications for the biology of opiate tolerance and addiction

This does not necessarily mean the peptide is dangerous, but it means stated purity numbers should be taken with a grain of salt unless verified independently