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The resuspended cells were lysed by sonication using a Branson sonifier (3.2 mm tip) at 45% amplitude, with 10 s on/off pulses, for a total of 3 min

Reduces Melanin production, thus make skin comparatively fairer and radiant

published that short interfering RNA (siRNA) and Keap1 were involved in silencing the expression of Nrf2 in coronary arterial endothelial cells, leading to cellular proliferative capacity impairment, improper adhesion to extracellular matrix proteins, reduced migration, and impaired capillary formation (Valcarcel-Ares et al., 2012)